Open commons
Follow classic and contemporary science in the open — bring your own work, or start from ours.
Infrastructure for insight
Serious tools for the seriously curious.
Version control for AI-native and manual in silico science. Wet-lab / dry-lab handoff lossiness is a thing of the past. Create private, AI-enabled science workspaces for individuals or teams — unencumbered exploration and creativity. Open commons for shared and historically important discovery — keep your work in a walled garden, or share it with the world.
Version, branch, and review scientific work.
Studies keep checkpoints and entities attached — so the record stays readable, not a pile of files.
An open commons study — the public face of the same record model your private work uses.
Entity-aware tools — connected to your registries, catalogs & vaults
An account includes a Commonscience registry for your studies and sketches in the platform — or hook into systems you already trust. Same entity model either way.
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Life sciences
- CDD Vault
- Benchling Registry
- LabKey
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Physics & materials
- Materials Project
- HEPData
- COD / ICSD
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Math
- OEIS
- Lean mathlib
- NIST DLMF
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Engineering
- PLM / PDM vaults
- Ansys Granta MI
- Octopart
Exemplars — not exhaustive. Inventories, repositories, and part libraries count too.
Your tools
Bring your own AI and APIs. We help creativity and judgment — we don’t prescribe how to run an experiment.
Open studies you can follow
Browse commons- Chemistry · Biology Penicillin — From Contaminated Plate to Medicine A contaminated plate, careful noticing, and wartime scale-up into medicine.
- Physics Michelson–Morley — Looking for the Ether Wind A null result everyone expected to be positive — and a door into relativity.
- Chemistry · Medicine Factor Xa Inhibitors — Anticoagulant Series A multi-decade medchem trail from HTS hits to rivaroxaban, told as a study.
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How the model holds the work together
Folders don’t know a compound from a PDF. Commonscience treats scientific things as entities — typed objects with identity, history, and relationships — so the notebook can actually carry meaning across tools and people.
Typed identity, not filenames
A molecule, assay result, specimen, simulation, or note stays itself — who made it, what it depends on, how it changed. Search, reuse, and provenance attach to the object, not to whatever someone named a file.
Wet lab ↔ dry lab without the drop
In silico work and bench work reference the same entities. When a structure, sample, or result moves between modes, the context moves with it — instead of reconstituting the story from email and slides.
Handoffs that keep the graph
Passing work to a collaborator — or your future self — carries the same objects and relationships through GUIDE. Fewer “here’s a zip” moments; more of a shared record you can continue.